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Pharmacology is a branch of biology which studies drug actions at all levels and can provide important information for preclinical and clinical studies. The two main areas of pharmacology are pharmacodynamics and pharmacokinetics. Pharmacology studies are of great importance in determining the effect of lead compound during drug discovery and can provide key evidence for lead optimization and the selection of drug candidates for further development.
Creative Biolabs provides professional pharmacology studies for lead validation of drug discovery process thus to deal with data reproducibility crisis which is a big obstacle for drug research and development and may lead to failure and high risk of investment. With our professional pharmacology studies, we can drive forward and speed up your drug discovery process.
Creative Biolabs offers comprehensive pharmacology studies, including but not limited to the following:
Safety pharmacology satisfies a vital requirement in the drug development process. Safety pharmacology specializes in detecting and investigating any potential undesirable effects of drugs on the body’s major physiological systems in relation to dosage within the therapeutic range and above. Based on the results of safety pharmacology studies, corresponding strategies can be developed to advance drug candidates. We are highly qualified for providing you with comprehensive and efficient as well as economical safety pharmacology studies which can be used throughout your drug development process to help de-risk your candidates.
Pharmacodynamics (PD) is the study of the physiological and biochemical effects of drugs and to discover how the drug affects the organism. Pharmacodynamics particularly emphasizes on dose-response relationships. Successful drug candidates for clinical development require a safe and effective dosing regimen. Pharmacodynamic characterizations are important considerations for defining a dosing regimen. We provide various pharmacodynamic assays to support drug discovery and development.
Pharmacokinetics (PK) is a study of how an organism affects a drug by determining the mechanisms of a drug's absorption, biodistribution, metabolism and excretion (ADME). PK studies are of great importance in creating new therapeutic drugs, understanding both the beneficial and harmful effects of drug candidates, and guiding drug development experiments and trials. We apply our expertise in a variety of pharmacokinetic assays to support PK studies, and provide high-quality PK assay procedures and results to meet your requirements.
Drug Metabolism and Pharmacokinetics (DMPK)
Drug metabolism and pharmacokinetics (DMPK) is the study of drug disposition process in the organism, which use mathematical and dynamic models to describe the process of ADME, then combining the exposure of drugs in blood circulation and target organs with clinical manifestations (pharmacodynamics and toxic side effects). DMPK is important for the selection of highly developable candidates with good bioavailability and safety. We are specializing in offering comprehensive services for extensive drug metabolism and pharmacokinetic capabilities.
Creative Biolabs has a dedicated assay development team that will work closely with you to design customized assays. Our service will meet your specific needs fast at extremely competitive prices. If you need more information, please feel free to contact us at anytime. We look forward to working with you to help your drug research and development project succeed.
