Mesenchymal Stem Cell-based Therapy Development

Creative Biolabs brings together highly skilled experts with different backgrounds who have extensive experience in data validation and project evaluation of stem cell therapy. Each of our experts plays a key role in advancing our clients' projects and achieving superior results. With extensive expertise in the field of stem cell therapy, we provide comprehensive stem cell therapy data validation and project evaluation services to support the development of cell therapy.

Mesenchymal Stem Cell

Mesenchymal stem cells (MSCs) are adult stem cells found in the bone marrow and are responsible for bone and cartilage repair. They have the ability to self-renewal and differentiate into not only mesoderm lineages, such as chondrocytes, osteocytes and adipocytes, but also ectodermic cells and endodermic cells. MSCs exist in almost all tissues. They can be easily isolated from the bone marrow, adipose tissue, the umbilical cord, peripheral blood, fetal liver, muscle, and lung and can be successfully expanded in vitro.

MSCs Therapy

From animal models to clinical trials, MSC has broad prospects in treating a variety of diseases, mainly tissue and immune disorders. Currently, there are more than 800 MSC-based clinical trials in the United States designed to evaluate the potential of MSC-based cell therapy. Some of these studies include bone and cartilage diseases, diabetes, and osteoarthritis (Fig.1). MSCs have shown promising results in preclinical and clinical studies for treating pain and degenerative diseases such as Alzheimer's disease (AD), Degenerative disc disease (DDD), Multiple sclerosis (MS), Parkinson's disease (PD), and Rosai-Dorfman Disease (RDD) and providing immunomodulatory, neuroprotective, and anti-inflammatory responses. In addition, MSCs have the ability to exert anti-inflammatory and immunomodulatory effects and therefore are used to treat transplant rejection or autoimmune diseases. They can also regenerate mesenchymal tissues such as bone, cartilage, muscle, ligaments, tendons, and adipose and can be utilized for many beneficial purposes.

Mesenchymal Stem Cell-based Therapy Development Fig.1 Ongoing clinical trials based on mesenchymal stem cell therapy. (Brown, 2019)

Our Services

Creative Biolabs has more than 10 years of experience in providing high-quality outsourced data verification and data validation services. Our data validation experts can detect and correct any questionable or inaccurate data to improve the accuracy and reliability of data from MSCs therapy programs. In addition, Creative Biolabs' team of experts can provide MSCs treatment program design and tailored solutions to support your stem cell research. At Creative Biolabs, each service contract is assigned to a dedicated director who is available for consultation throughout your entire project.

Features:

Creative Biolabs will work with our customers to overcome any challenges in stem cell therapy development. We provide 24×7 customer support, you can contact us at any time to inquire about your data verification and data validation outsourcing needs.

Reference

  1. Brown, C.; et al. Mesenchymal stem cells: Cell therapy and regeneration potential. Journal of tissue engineering and regenerative medicine. 2019, 13(9): 1738-1755.
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