Sequencing Services

Sequencing services aim at identifying key targets, characterizing specific gene functions and describing networks of related diseases. These human origin data contain information of DNA sequence as well as genetic relationships, origin or susceptibility to specific drugs can provide a first valid hint to a certain condition.

Creative Biolabs provides sequencing services for target validation of drug discovery process thus to deal with data reproducibility crisis which is a big obstacle for drug research and development and may lead to failure and high risk of investment.

Creative Biolabs offers various sequencing services, including but not limited to the following:

Whole Genome Sequencing

Whole genome sequencing (WGS), also known as full genome sequencing or complete genome sequencing, is the process to determine the order of the nucleotides (A, C, G, T) in the entire genome that makes up an organism at a single time. It sequences not only all of chromosomal DNA but also mitochondrial DNA. WGS represents the ultimate step in assaying human genetic variation at the base sequence level. The development of WGS, combined with the falling cost of the technology holds great promise for accelerating the delivery of genetic predictors of human diseases and related treatment. We offers different possibilities for whole genome sequencing, especially advanced SuPrecision™ platform, to provide an accurate and high-throughput sequencing service to help you investigate key target genes and characterize specific gene functions.

Whole Exome Sequencing

Whole exome sequencing (WES) is a genomic technique for sequencing the exome which are the part of the genome formed by exons or coding regions and can be transcribed and translated into proteins. WES aims at identifying genetic variants that alter protein sequences. WES can sequence exomes which compose only about 2% of the whole genome at a much greater depth for lower cost compared to WGS. We can offer high-quality WES service with our extensive experience and advanced platform to satisfy each demand from our clients.

Whole Transcriptome Sequencing

Whole transcriptome sequencing (WTS) is a next generation sequencing technique that offers a snapshot measurement of the complete transcripts including mRNA and all non-coding RNA in a cell at a given moment in time. The regulation of transcription level is the most studied and the most important way of regulation in organisms. WTS can accurately measure transcript abundance, and identify known and novel features of the transcriptome. WTS has the potential to identify new disease biology and infer druggable pathways. We are dedicated to providing the best WTS service with our latest technologies.

Targeted Sequencing

Targeted sequencing is a rapid and cost-effective next-generation sequencing (NGS) technique focusing on amplicons and specific genes to detect known and novel variants in selected sets of genes or genomic regions and can offer unique insights into specific regions of interest in the genome. Targeted sequencing is useful in population genetics and is a powerful tool to investigate a variety of disease areas. Utilizing NGS technology, it can accurately and effectively locate specific genes, coding regions and even chromosome segments that are directly relevant. Targeted sequencing is an effective approach to increase the cost-effectiveness compared to WGS, and is helpful for further analysis of the results of WGS and other survey approaches. We are confident to provide high-quality targeted sequencing service to facilitate our clients’ genomics research and drug development project.

Gene Expression Profiling

Gene expression profiling can create a global picture of cellular function by the measurement of the activity of thousands of genes at once. This technology can provide accurate information on gene expression and achieve numerous experimental goals. With highly qualified and experienced molecular biologists, geneticists, and bioinformaticians, we provide comprehensive gene expression profiling service to help our clients identify and validate drug targets.

Creative Biolabs has a dedicated assay development team that will work closely with you to design customized assays. Our service will meet your specific needs fast at extremely competitive prices. If you need more information, please feel free to contact us at anytime. We look forward to working with you to help your drug research and development project succeed.